Background: Because of the world obesity epidemic, some type 1 diabetics exhibit clinical-biological features of metabolic syndrome. Few studies have investigated the association between this syndrome and this type of diabetes.
Aim: To estimate the prevalence of metabolic syndrome in type 1 diabetics and to study the relationship between this syndrome and the clinical-biological profile of these patients.
Methods: We carried out a cross-sectional study, involving type 1 diabetics, monitored at the National Institute of Nutrition in Tunis. All of these patients underwent a clinical examination and laboratory workup.
Results: We included 150 patients. The mean age of the patients was 31.25 ± 10.3 years. Women represented 54% of the patients. Abdominal obesity was found in 61.7% of women and 14.5% of men. The metabolic syndrome was found in 30.7% of patients, with a female predominance (48.1% vs. 10.1% in men, p <0.001). Comparing the two groups with and without metabolic syndrome, the latter was significantly correlated with sedentary lifestyle, daily insulin dose, hypertriglyceridemia, hypoHDL-cholesterolemia and arterial hypertension, but not correlated with the age of the patients, the duration of diabetes or the glycemic control.
Conclusion: This work reveals a high prevalence of metabolic syndrome in type 1 diabetics in whom it seems relevant to look for the components of this syndrome, each considered to be a cardiovascular risk factor in its own right.
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