Whilst schwannomas are mostly developed in the head neck area, the sinonasal involvement is extremely rare, especially those of the frontal sinus. We report a patient with sinonasal schwannoma, invading both frontal sinuses, anterior cranial fossa, the left anterior ethmoidal sinus, and the left nasal cavity. Radiologic imaging showed an isodensed, T2 isointense, T1 hypointense, with heterogeneous enhanced postcontrast mass with bone destruction. The patient underwent resection of the tumor via two approaches, external one and endonasal one. The histological diagnosis was consistent with a schwannoma. The follow-up was marked by the presence of diplopia without any signs of meningitis or cerebrospinal fluid rhinorrhoea.
N. Subramanian, N. Sood, and W. Ramalingam, “Large Sinonasal Schwannoma with Skull Base Defect: A Case Report,” Indian J Otolaryngol Head Neck Surg, 2019. 71(Suppl 1): p. 887-889.
Zhou, H., et al., “Schwannoma of the Sinonasal Tract and the Pterygopalatine Fossa with or without Intracranial Extension,” ORL J Otorhinolaryngol Relat Spec, 2015. 77(2): p. 61-9.
Mangubat, E.Z., et al., “Frontal sinus schwannoma: case report and review of literature,” Skull Base Rep, 2011. 1(1): p. 17-22.
Kumar, S. and C. Sayoo, “Sinonasal Schwannoma: A Rare Sinonasal Neoplasm,” Indian J Otolaryngol Head Neck Surg, 2017. 69(3): p. 425-427
Iyer, A., et al., “Schwannomas of the Frontal Sinus: Cases and Review of the Literature,” World Neurosurg, 2018. 110: p. 485-491.
Sunaryo, P.L., et al., “Schwannomas of the sinonasal tract and anterior skull base: a systematic review of 94 cases,” Am J Rhinol Allergy, 2014. 28(1): p. 39-49.
Gencarelli, J., et al., “Atypical presentation of sinonasal cellular schwannoma: a nonsolitary mass with osseous, orbital, and intracranial invasion,” J Neurol Surg Rep, 2014. 75(1): p. e144-8.
Blake, D.M., et al., “Endoscopic endonasal resection of sinonasal and anterior skull base schwannomas,” J Clin Neurosci, 2014. 21(8): p. 1419-23.