A Case of Sinonasal Squamous Cell Carcinoma with Secondary Involvement of the Orbit

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We report clinical characteristic, imaging studies, and management of a rare case of expansion epithelial malignancy due to squamous cell carcinoma (SCC). A man was admitted with protrusion of the left eye due to orbital medial tumor mass. The patient had undergone removal surgery, chemotherapy, and radiotherapy two years ago. Imaging and histopathological studies were conducted to determine protrusion of the left eye due to Non-keratinizing sinonasal SCC. The left eye exenteration was conducted and continued with the chemotherapy procedure. This case demonstrates that even aggressive and repetitive surgical may not be adequate in preventing worse outcomes.

  1. Marrazzo G, Zitelli JA, and Brodland D. Clinical outcomes in high-risk squamous cell carcinoma patients treated with Mohs micrographic surgery alone. American Academy of Dermatology, Inc. jaad.2018.09.015.
     Google Scholar 
  2. V. Saloura, et al. Immune profiles in primary squamous cell carcinoma of the head and neck. Oral Oncology 96 (2019) 77–88.
    DOI
     Google Scholar 
  3. Oliver JR, et al. Human Papillomavirus and Survival of Patients with Sinonasal Squamous Cell Carcinoma. Willey Online. DOI 2019: 10.1002/cncr.32679.
    DOI
     Google Scholar 
  4. Sanghvi S, Khan MN, Patel NR, Yeldandi S, Baredes S, Eloy JA. Epidemiology of sinonasal squamous cell carcinoma: a comprehensive analysis of 4994 patients. Laryngoscope. 2014; 124:76-83.
    DOI
     Google Scholar 
  5. Kilic S, Shukla PA, Marchiano EJ, et al. Malignant primary neoplasms of the nasal cavity and paranasal sinus. Curr Otorhinolaryngol Rep. 2016; 4:249-258.
    DOI
     Google Scholar 
  6. Kilic S, Kilic SS, Kim ES, et al. Significance of human papillomavirus positivity in sinonasal squamous cell carcinoma. Int Forum Allergy Rhinol. 2017; 7:980-989.
    DOI
     Google Scholar 
  7. Tailor TD, Gupta D, Dalley RW, Keene CD dan Anzai Y. Orbital Neoplasms in Adults: Clinical, Radiologic, and Pathologic Review. Radiographics.rsna.org. 2013: 1739-1759.
    DOI
     Google Scholar 
  8. Ushalatha B dan Sambasivarao. Role of CT in the Evaluation of Orbital Tumors. IOSR-JDMS. 2016; 15(4):16-19.
     Google Scholar 
  9. Shanthi Marur, and Arlene A. Forastiere. Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment. Mayo Clin Proc. 2016;91(3):386-396
    DOI
     Google Scholar 
  10. Pfortner R, Mohr C, Daamen J, dan Metz A. Orbital Tumors: Operative and Therapeutic Strategies. Facial Plast Surg. 2014(30): 570-577.
    DOI
     Google Scholar 

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How to Cite

Yuliawati, P., & Lestari, N. P. D. (2021). A Case of Sinonasal Squamous Cell Carcinoma with Secondary Involvement of the Orbit. European Journal of Medical and Health Sciences, 3(1), 18–20. https://doi.org/10.24018/ejmed.2021.3.1.656

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