Toxic Anterior Segment Syndrome (TASS)


  •   Sidi Dahi

  •   Mehdi Khamaily

  •   Joumany Brahim Salem

  •   Wafae Akioud

  •   Houda Brarou

  •   Taoufik Abdellaoui

  •   Yassine Mouzari

  •   Karim Reda

  •   Abdelbarre Oubaaz


Cataract surgery is ranked among the most frequent operations, affecting a population over 65 years of age.Its prognosis is often favorable, however, there are rare complications including inflammation of the anterior segment known as Anterior Segment Toxicity Syndrome . the majority of our patients were men and diabetes appear in almost half and all our patients present various symptoms the first 24 hours dominated by the attack of the anterior segment our therapeutic attitude consists in the use of corticosteroids and hypotonizers with a good evolution in the majority of patients.

Keywords: phacoemulsification, inflammation, Corticosteroid


Anusha Koshal Ram, Bala Subramanian Toxic Anteriorsegment Syndrome Presenting as Endothelitis Following Uneventful Phaco Emulsification TNOA Journal of Ophthalmic Science and Research ¦ Volume 56 ¦ Issue 2 ¦ April-June 2018.

Chiquet C and al. Eubacterial PCR for bacterial detection and identification in 100 acute postcataract surgery endophthalmitis Invest Ophthalmol Vis Sci 2008; 49.

Moyle W, Yee RD, Burns JK, Biggins T. Two consecutive clusters of toxic anterior segment syndrome. Optom Vis Sci. 2013;90(1):e11–23.

Mamalis N. Toxic anterior segment syndrome: role of enzymatic detergents used in the cleaning of intraocular surgical instruments. J Cataract Refract Surg. 2016;42(9):1249–50.

Braga-Mele. Intracameral antibiotics: safety, efficacy, and preparation. J Cataract Refract Surg. 2014;40(12):2134–42.

Andonegui J, Outbreak of toxic anterior segment syndrome after vitreous surgery. Arch Soc Esp Oftalmol. 2009;84(8):403–5.

Matsou A, et al Generic trypan blue as possible cause of a cluster of toxic anterior segment syndrome cases after uneventful cataract surgery. J Cataract Refract Surg. 2017;43(6):848–52.

Buzard K, et al. Two cases of toxic anterior segment syndrome from generic trypan blue. J Cataract Refract Surg. 2010;36(12):2195–9.

Althomali TA. Viscoelastic substance in prefilled syringe as an etiology of toxic anterior segment syndrome. Cutan Ocul Toxicol. 2016;35(3):237–41.

Oshika T, Eguchi S, Goto H, Ohashi Y. Outbreak of subacute-onset toxic anterior segment syndrome associated with single-piece acrylic intraocular lenses. Ophthalmology. 2017; 124:519–23.

Yazgan S, et al: The role of patient's systemic characteristics and plateletcrit in developing toxic anterior segment syndrome after uneventful phaco surgery: a case-control study. Int Ophthalmol. 2018;38(1):43–52.

Most read articles by the same author(s)

1 2 > >>