Ocular Pemphigus Vulgaris

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  •   Mehdi Khamaily

  •   Joumany Brahim Salem

  •   Houda Brarou

  •   Sidi Dahi

  •   Abdelhadi Omari

  •   Yassine Mouzari

  •   Fouad El Asri

  •   Karim Reda

  •   Abdelbarre Oubaaz

Abstract

Introduction: Pemphigus vulgaris is a rare intra-epidermal autoimmune dermatosis, characterized by bullous cutaneous and mucosal involvement. Ocular involvement is relatively rare, of which blepharitis or conjunctivitis with hyperemia and secretions are the most described lesions


Methods: we report the case of a patient, who was hospitalized in dermatology for dermatological pemphigus with ocular involvement.


Results: the patient presented an erosive bilateral cutaneous-palpebral lesions with purulent secretions associated with conjunctival hyperemia


Conclusion: Ocular involvement in the common pemphigus remains an exception, the prognosis of which is often mild.


Keywords: Pemphigus, blepharitis, ocular surface, autoimmune diseases

References

Eming R, et al. S2k guidelines for the treatment of pemphigus vulgaris/foliaceus and bullous pemphigoid. J Dtsch Dermatol Ges 2015; 13: 833–44. DOI: https://doi.org/10.1111/ddg.12606

Elchahal S et al. Ocular manifestations of blis¬tering diseases. Immunol Allergy Clin N Am 2008; 28: 119–36. DOI: https://doi.org/10.1016/j.iac.2007.12.002

Brackley R, Pagani JM. Conjunctival erosions associated with pemphigus vulgaris. Optom Vis Sci 2011; 88: 1010–3. DOI: https://doi.org/10.1097/OPX.0b013e31821ddef3

Palleschi G.M.et al. Ocular involvement in Pemphigus. Am J Ophtalmol 2007; 144:149-52. DOI: https://doi.org/10.1016/j.ajo.2007.02.046

Agustin España, Pilar Iranzo, Josep Herrero-González, José M. Mascaro Jr., Ricardo Suárez. Ocular involvement in pemphigus vulgaris – a retrospective study of a large Spanish cohort. Deutsche Dermatologische Gesellschaft (DDG). Ltd. | JDDG | 1610-0379/2017. DOI: https://doi.org/10.1111/ddg.13221

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