Flexible Insulin Therapy: Results of a Tunisian Experience

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  •   Hajer Kandara

  •   Chaima Jemai

  •   Abdennebi Cyrine

  •   Jemel Manel

  •   Kammoun Ines

Abstract

Aims: To evaluate the adherence of type 1 diabetic patients to long-term flexible insulin therapy (FIT), and the impact of this approach on the glycemic balance, basal insuline dose and quality of life of patients.


Methods: This is a rospective descriptive study, conducted between January and April 2017, including 50 patients with type 1 diabetes having following the FIT of department B of Endocrinology-Diabetology and Metabolic Diseases service B at the National Institute of Nutrition and Food Technology of Tunis.


Results: The FIT decreased mean HbA1c from 8.96% to 7.57% (p=0.04) and mean basal insulin dose from 0.35 to 0.27 IU/kg /day. Hypoglycemia's frequency decreased from 3.2±2.1 to 0.93±2.1 episodes /patient /week (p=0.03), with improved quality of life. However, there was a significant weight gain (p=0.02).


Conclusions: FIT allows for better glycemic control while reducing hypoglycemia, especially severe episodes, and improves the quality of life of patients with type 1 diabetes but seems to cause weight gain.


Keywords: Flexible Insulin therapy; Type 1 Diabetes; Therapeutic education; Blood glucose.

References

Aims: To evaluate the adherence of type 1 diabetic patients to long-term flexible insulin therapy (FIT), and the impact of this approach on the glycemic balance, basal insuline dose and quality of life of patients.

Methods: This is a rospective descriptive study, conducted between January and April 2017, including 50 patients with type 1 diabetes having following the FIT of department B of Endocrinology-Diabetology and Metabolic Diseases service B at the National Institute of Nutrition and Food Technology of Tunis.

Results: The FIT decreased mean HbA1c from 8.96% to 7.57% (p=0.04) and mean basal insulin dose from 0.35 to 0.27 IU/kg /day. Hypoglycemia's frequency decreased from 3.2±2.1 to 0.93±2.1 episodes /patient /week (p=0.03), with improved quality of life. However, there was a significant weight gain (p=0.02).

Conclusions: FIT allows for better glycemic control while reducing hypoglycemia, especially severe episodes, and improves the quality of life of patients with type 1 diabetes but seems to cause weight gain.

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How to Cite
Kandara, H., Jemai, C., Cyrine, A., Manel, J., & Ines, K. (2020). Flexible Insulin Therapy: Results of a Tunisian Experience. European Journal of Medical and Health Sciences, 2(4). https://doi.org/10.24018/ejmed.2020.2.4.243