Recently, a method for assigning the probability of disease onset to all people, those clinically ill as well as those without prevalent disease has been described and termed the Oxidative Stress Index (OSI). The OSI, as originally formatted, does not predict which disease will more likely develop, only that further disease is predicted with increased OSI. It is hypothesized here that the OSI may be used to demonstrate which parameters are more contributory to the onset of a particular disease if it is measured at the time of onset of that disease. To test this hypothesis, the OSI has been reformatted to serve in that capacity for Alzheimer's disease (AD) with the anticipation that the OSI could serve to predict not only the likelihood of onset, but also identify those parameters that are most contributory to AD.
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