COVID-19 in India: Breakthrough Infections in Delta Wave


  •   Zameer Shervani

  •   Roma Nikhat

  •   Sadia Hasan

  •   Umair Yaqub Qazi

  •   Kehkeshan Fatma

  •   Arif Siddiquie

  •   Venkata Phani Sai Reddy Vuyyuru

  •   Nudrat Jamal

  •   Aiman Ibbrahim

  •   Samar Siddiqui

  •   Adil Ahmed Khan

  •   Parangimalai Diwakar Madan Kumar

  •   Manseej Purang

  •   Ankira Agarwal


The breakthrough infections (BTI) during the Delta wave in the general population have been investigated. The BTI reported in the city of Gurugram (Haryana, India) in the month of August, September, and October 2021 were studied. The monthly BTI in August, September, and October 2021 were 26%, 41%, and 76%, which caused an increase in the monthly caseload to 167, 150, and 206 cases, respectively. Mostly, the patients who had comorbidities developed BTI. However, the BTI reported in the Delta wave did not cause a surge in new cases. The surge was noticed only after the emergence of the Omicron variant of the SARS- CoV-2 virus. In Gurugram, 78.3% sero prevalence recorded in September 2021 was due to vaccination and higher infection rate of 59,921 monthly cases reported in April 2021.

Keywords: Delta variant, Omicron pathogenicity, Omicron prevalence and transmissibility, Omicron variant, SARS-CoV-2 mutation


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