Giant Invasive Pituitary Adenoma Differential Diagnosis and Therapeutic Management (A Case Report and Literature Review)

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  •   Abderrahmane Rafiq

  •   Liévin Panu

  •   Abdelhamid Jehri

  •   Tarek Mesbahi

  •   Abdelhakim Lakhdar

Abstract

Giant pituitary adenomas represent a significant surgical and diagnostic challenge; giant pituitary adenomas with a development that goes beyond the sella can be difficult to manage surgically due to the narrowness of the space and the proximity of important anatomical structures which are at risk according to the surgical approach and its extension in the cavum with absence of endocrine sign can be misinterpreted as cancer of the cavum which was the case for our patient refer to the neurosurgery department after 3 inconclusive biopsies by nasofibroscopy and after visual deterioration.


Keywords: Case report, endoscopy endonasal surgery, giant, invasive, pituitary adenoma

References

Goel A, Nadkarni T. Surgical management of giant pituitary tumours—a study of 30 cases. Acta Neurochir (Wien). 1996; 138: 1042-1049.

Goel A, Nadkarni T, Muzumdar D, Desai K, Phalke U, Sharma P. Giant pituitary tumors: a study based on surgical treatment of 118 cases. Surg Neurol. 2004; 61: 436-445.

Kaltsas GA, Nomikos P, Kontogeorgos G, Buchfelder M, Grossman AB. Clinical review: diagnosis and management of pituitary carcinomas. J Clin Endocrinol Metab. 2005; 90: 3089-3099.

Knosp E, Steiner E, Kitz K, Matula C. Pituitary Adenomas with Invasion of the Cavernous Sinus Space. Neurosurgery. 1993; 33: 610–617.

Gondim JA, Almeida JPC, Albuquerque LAF, Gomes EF, Schops M. Giant pituitary adenomas: surgical outcomes of 50 cases operated on by the endonasal endoscopic approach. World Neurosurgery. 2014; 82(1-2): e281-e290.

Koutourousiou M, Gardner PA, Fernandez-Miranda JC, Paluzzi A, Wang EW, et al. Endoscopic endonasal surgery for giant pituitary adenomas: advantages and limitations. Journal of Neurosurgery, 2013; 118(3): 621-631.

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How to Cite
Rafiq, A. ., Panu, L., Jehri, A., Mesbahi, T., & Lakhdar, A. (2022). Giant Invasive Pituitary Adenoma Differential Diagnosis and Therapeutic Management (A Case Report and Literature Review). European Journal of Medical and Health Sciences, 4(1), 35–37. https://doi.org/10.24018/ejmed.2022.4.1.1137