Literature Review of Epidemiological Phenomena: Corona Virus Disease Pandemic 2019


  •   Yarmaliza Yarmaliza

  •   Teungku Nih Farisni

  •   Fitriani Fitriani

  •   Zakiyuddin Zakiyuddin

  •   Fitrah Reynaldi

  •   Safrizal Safrizal

  •   Lili Eky Nursia N


Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or Corona virus is a new type of coronavirus that is transmitted to humans. Corona virus infection called COVID-19 (Corona Virus Disease 2019) was first discovered in the city of Wuhan, China at the end of December 2019. Until March 2, 2020, more than 80 thousand confirmed cases have been reported in China. Of these cases, 49 thousand were identified in Wuhan City. Epidemiologically, the spread or distribution of this disease has a wide social and economic impact on the world. Many literature studies about the COVID-19 outbreak, such as causes, natural history of the disease, even to the preventive and medical treatment. Since the end of 2019 until April 2020, there have been many published literature or literature studies at both national and international levels, so this paper aims to examine literature studies related to COVID-19.

Keywords: COVID 19, Epidemiology, Pandemic


Kementerian Kesehatan RI. 2020. Pedoman Kesiapsiagaan Menghadapi Infeksi Novel Coronavirus (2019-nCoV). Jakarta.

Kementerian Kesehatan RI. “Kementerian Kesehatan Tegaskan Belum Ada Kasus di Indonesia”, Suara Pembaruan, 27 Januari 2020, hal. 12.

Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The reproductive number of COVID-19 is higher compared to SARS coronavirus. J Travel Med. 2020;27(2).

Xu,X.T.;Chen,P.;Wang,J.F.;Feng,J.N.;Zhou,H.;Li,X.;Zhong,W.;Hao,P.Evolution of the novel corona virus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci.China Life Sci. 2020.

Wuhan Municipal Health Commission. Report on the Current Situation of Pneumonia in Wuhan (2020-01-11).

World Health Organization. Coronavirus disease 2019 (COVID-19) Situation Reports. Available online: (accessed on19 February 2020).

National Health Commission of the People’s Republic of China and National Administration of Traditional Chinese Medicine. Diagnosis & Treatment Scheme for Novel Coronavirus Pneumonia (Trial) 6th Edition. Available online: (accessed on 19 February 2020).

Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395:507-513.

Ki, M. and V.T. nCo, Epidemiologic characteristics of early cases with 2019 novel coronavirus (2019-nCoV) disease in Republic of Korea. Epidemiol Health, 2020: p. e2020007.

Guan, Y., et al., Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science, 2003. 302(5643): p. 276-8.

WHO, Coronavirus disease (COVID-19) advice for the public: Myth busters. Avialble at ( 2020.

Otter, J.A., et al., Transmission of SARS and MERS coronaviruses and influenza virus in healthcare settings: the possible role of dry surface contamination. J Hosp Infect, 2016. 92(3): p. 235-50.

Li G, Fan Y, Lai Y, Han T, Li Z, Zhou P, et al. Coronavirus infections and immune responses. J Med Virol 2020;92:424e32.

Fan YY, Huang ZT, Li L, Wu MH, Yu T, Koup RA, et al. Characterization of SARS-CoV-specific memory T cells from recovered individuals 4 years after infection. Arch Virol. 2009;154(7):1093-9.

Zhou P, Yang X-L, Wang X-G, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020;579(7798):270-3.

Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020;395(10226):809-15.

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. New Engl J Med. 2020; published online February 28. DOI: 10.1056/ NEJMoa2002032.

World Health Organization. Clinical management of severe acute respiratory infection when novel coronavirus (nCoV) infection is suspected. Geneva: World Health Organization; 2020.

Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; published online March 20. DOI: 10.1016/S2468-1253(20)30084-4.

World Health Organization. Home care for patients with COVID-19 presenting with mild symptoms and management of their contacts. Geneva: World Health Organization; 2020.

World Health Organization. Coronavirus disease (COVID-19) advice for the public [Internet]. 2020 [cited 2020 March 15]. Available from: novel-coronavirus-2019/advice-for-public.

Roth DE, Richard SA, Black RE. Zinc supplementation for the prevention of acute lower respiratory infection in children in developing countries: meta-analysis and meta-regression of randomized trials. Int J Epidemiol. 2010;39(3):795-808.

Department of Health and Social Care, Public Health England. Coronavirus: latest information and advice . GOV.UK , 2020 . www.

Chen N, Z hou M , Dong X et al. E pidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020.

Rothe C, Schunk M, Sothmann P et al. Transmission of 2019-nCoV infection from an asymptomatic contact in Germany. N Engl J Med 2020.

Biggerstaff M, Cauchemez S, Reed C, Gambhir M, Finelli L. Estimates of the reproduction number for seasonal, pandemic, and zoonotic influenza: a systematic review of the literature . BMC Infect Dis 2014 ; 14 : 480.

Chan JF, Yuan S, Kok KH et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-toperson transmission: a study of a family cluster . Lancet 2020.

Public Health England. Investigation and initial clinical management of possible cases of Wuhan novel coronavirus (2019-nCoV) infection. GOV.UK, 2020.

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, Wang B, Xiang H, Cheng Z, Xiong Y, Zhao Y, Li Y, Wang X, Peng Z. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020 Feb 7.

Momattin H, Al-Ali AY, Al-Tawfiq JA. A Systematic review of therapeutic agents for the treatment of the Middle East respiratory syndrome coronavirus (MERS-CoV). Travel Med Infect Dis 2019; 30: 9–18.


Download data is not yet available.


How to Cite
Yarmaliza, Y., Farisni, T., Fitriani, F., Zakiyuddin, Z., Reynaldi, F., Safrizal, S., & Nursia N, L. (2020). Literature Review of Epidemiological Phenomena: Corona Virus Disease Pandemic 2019. European Journal of Medical and Health Sciences, 2(3).